DLGAP1 anticorps (AA 241-360)

N° du produit ABIN1387960

Cet anticorps Lapin Polyclonal détecte spécifiquement DLGAP1 dans ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour DLGAP1 anticorps (AA 241-360) (ABIN1387960)

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DLGAP1 anticorps

Épitope: AA 241-360

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SAPAP1/DLGAP1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DLGAP1

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Autre désignation: SAPAP1/DLGAP1

Sujet:

Synonyms: PSD95 binding protein 1, DAP 1 ALPHA, DAP 1, DAP 1 BETA, DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, Discs large Drosophila homolog associated protein 1, Discs large homolog associated protein 1, Disks large associated protein 1, Disks large associated protein 1, alpha isoform, included, Disks large associated protein 1, beta isoform, included, Disks large-associated protein 1, DLGAP 1, Dlgap1, DLGP1_HUMAN, GKAP, GKAP/SAPAP, GKPA/SAPAP, Guanylate kinase associated protein, Guanylate kinase-associated protein, hGKAP, KIAA4162, MGC88156, mKIAA4162, PSD 95/SAP90 binding protein 1, PSD-95/SAP90-binding protein 1, SAP90/PSD 95 associated protein 1, SAP90/PSD-95-associated protein 1, SAPAP 1, SAPAP1.

Background: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.