Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (AA 10-60) anticorps

N° du produit ABIN1387969

Cet anticorps Lapin Polyclonal détecte spécifiquement dans IHC (p) et IF (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (AA 10-60) anticorps (ABIN1387969)

Antigène: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 10-60

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Hemoglobin alpha

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Autre désignation: HBA1+HBA2

Sujet:

Synonyms: HBH, HBA-T3, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008].

ID gène: 3039

UniProt: P69905