CACNA1G/CACNA1H (AA 311-420) anticorps

N° du produit ABIN1387983

Cet anticorps anti-CACNA1G/CACNA1H Polyclonal Lapin (ABIN1387983) détecte spécifiquement CACNA1G/CACNA1H dans IF (cc), IF (p), ELISA, IHC (fro), IHC (p) et ICC. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour CACNA1G/CACNA1H (AA 311-420) anticorps (ABIN1387983)

Antigène: CACNA1G/CACNA1H

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit

Épitope: AA 311-420

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from CACNA1G + CACNA1H

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CACNA1G/CACNA1H

Autre désignation: CACNA1G + CACNA1H

Sujet:

Synonyms: Cav3.1c, Low voltage activated calcium channel alpha1 3.2 subunit, NBR13, Voltage dependent T type calcium channel subunit alpha 1G, Voltage dependent T type calcium channel subunit alpha 1H, Voltage gated calcium channel subunit alpha Cav3.1, Voltage gated calcium channel subunit alpha Cav3.2, CAC1G_HUMAN, CAC1H_HUMAN.

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. There are 2 isoforms of CACNA1H and 14 isoforms if CACNA1G, produced by alternative splicing.