DNMBP anticorps (AA 1101-1300)
Aperçu rapide pour DNMBP anticorps (AA 1101-1300) (ABIN1387993)
Antigène
Voir toutes DNMBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1101-1300
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human DNMBP
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- DNMBP (Dynamin Binding Protein (DNMBP))
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Autre désignation
- Dnmbp
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Sujet
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Synonyms: Dnmbp, DNMBP_HUMAN, Dynamin binding protein, Dynamin-binding protein, KIAA1010, Scaffold protein TUBA, TUBA.
Background: DNMBP, also known as Scaffold protein TUBA, is a 1,577 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, cell junction and Golgi apparatus, and contains one BAR domain, one DH domain and six SH3 domains. Expressed in kidney, heart, lung, liver, brain, pancreas and skeletal muscle, Tuba functions as a scaffold protein that links Dynamin with Actin-regulating proteins and is thought to play a role in protein trafficking between the golgi and the cell surface. Two isoforms of Tuba exist due to alternative splicing events. The gene encoding Tuba maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
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ID gène
- 23268
Antigène
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