CD235b/GYPB anticorps (AA 21-91) (AbBy Fluor® 488)

N° du produit ABIN1388326

Cet anticorps Lapin Polyclonal détecte spécifiquement CD235b/GYPB dans IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CD235b/GYPB anticorps (AA 21-91) (AbBy Fluor® 488) (ABIN1388326)

Antigène: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD235b/GYPB est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CD235b/GYPB anticorps (AbBy Fluor® 488)

Épitope: AA 21-91

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Glycophorin B

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CD235b/GYPB

Antigène: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Autre désignation: GYPB

Sujet:

Synonyms: SS, GPB, MNS, PAS-3, CD235b, GPB.NY, HGpMiX, GpMiIII, HGpMiVI, GYPHe.NY, HGpMiIII, Glycophorin-B, SS-active sialoglycoprotein, Sialoglycoprotein delta, GYPB

Background: Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains seven exons which are 97 % homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.

ID gène: 2994

UniProt: P06028