LRRTM1 anticorps (AA 151-250) (Biotin)

N° du produit ABIN1389943

Détail du produit anti-LRRTM1 anticorps (Biotin)

Antigène: LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))

Épitope: AA 151-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRTM1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LRRTM1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur LRRTM1

Antigène: LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))

Autre désignation: LRRTM1 (LRRTM1 Produits)

Synonymes: anticorps im:6904481, anticorps 4632401D06Rik, anticorps AW125451, anticorps leucine rich repeat transmembrane neuronal 1, anticorps lrrtm1, anticorps LRRTM1, anticorps Lrrtm1

Sujet:

Synonyms: Leucine rich repeat transmembrane neuronal 1, Leucine rich repeat transmembrane neuronal 1 protein, Leucine-rich repeat transmembrane neuronal protein 1, LRRT1_HUMAN, LRRTM1, Lrrtm1 leucine rich repeat transmembrane neuronal 1, OTTHUMP00000194829, 4632401D06Rik, AW125451, FLJ32082.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.

Pathways: Synaptic Membrane