Synaptojanin 2 anticorps (AA 401-500) (Biotin)

N° du produit ABIN1390915

Cet anticorps Lapin Polyclonal détecte spécifiquement Synaptojanin 2 dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Synaptojanin 2 anticorps (AA 401-500) (Biotin) (ABIN1390915)

Antigène: Synaptojanin 2 (SYNJ2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptojanin 2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Synaptojanin 2 anticorps (Biotin)

Épitope: AA 401-500

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Synaptojanin 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Synaptojanin 2

Antigène: Synaptojanin 2 (SYNJ2)

Autre désignation: Synaptojanin 2

Sujet:

Synonyms: 5-trisphosphate 5-phosphatase 2, Inositol phosphate 5' phosphatase 2, INPP 5H, INPP5H, KIAA0348, MGC44422, SJ2, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2, Synaptic inositol-1, Synaptojanin-2, Synaptojanin2, SYNJ 2, Synj2, SYNJ2_HUMAN.

Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.

ID gène: 8871

Pathways: Inositol Metabolic Process