HSD17B8 anticorps (AA 174-220) (FITC)

N° du produit ABIN1391096

L’anticorps Lapin Polyclonal anti-HSD17B8 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter HSD17B8 dans des échantillons de Souris.

Aperçu rapide pour HSD17B8 anticorps (AA 174-220) (FITC) (ABIN1391096)

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B8 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-HSD17B8 anticorps (FITC)

Épitope: AA 174-220

Réactivité croisée: Souris

Homologie: Human,Rat,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSD17B8

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HSD17B8

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Autre désignation: HSD17B8

Sujet:

Synonyms: 17 beta HSD 8, 17 beta hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 17-beta-hydroxysteroid dehydrogenase 8, 3-oxoacyl-[acyl-carrier-protein] reductase, Beta ketoacyl [acyl carrier protein] reductase like, D6S2245E, DHB8_HUMAN, dJ1033B10.9, Estradiol 17 beta dehydrogenase 8, Estradiol 17-beta-dehydrogenase 8, Estrogen 17 oxidoreductase, FABG, FABGL, H2 KE6, HKE6, HSD17B8, Hydroxysteroid 17 beta dehydrogenase 8, 17beta hydroxysteroid dehydrogenase type 8, Ke-6, KE6, Protein Ke6, Really interesting new gene 2 protein, RING2, SDR30C1, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17 beta dehydrogenase 8, Testosterone 17-beta-dehydrogenase 8.

Background: 17beta-HSD8 belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue. 17beta-HSD8 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and Testosterone. 17beta-HSD8 is predominantly expressed in placenta, endometrium and prostate but can also be found in liver, and pancreas, with lowest levels found in testis, ovary and kidney. It has been proposed that a reduction in the levels of 17beta-HSD8 may lead to abnormal elevations in the local level of sex steroids, which can lead to recessive renal cystic disease. It has also been suggested that low levels of 17beta-HSD proteins may result in an underdeveloped urogenital system.

ID gène: 7923

Pathways: Steroid Hormone Biosynthesis