FADS2 anticorps (Biotin)

N° du produit ABIN1391731

Cet anticorps Lapin Polyclonal détecte spécifiquement FADS2 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour FADS2 anticorps (Biotin) (ABIN1391731)

Antigène: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FADS2 est conjugé à/à la Biotin

Application: Western Blotting (WB)

Détail du produit anti-FADS2 anticorps (Biotin)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FADS2

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-1000), IHC-P(1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FADS2

Antigène: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Autre désignation: Fads2

Sujet:

Synonyms: D6D, Delta6 desaturase, Delta6 fatty acid desaturase, DES 6, DES6, FADS 2, FADSD 6, FADSD6, Fatty acid desaturase 2, linoleoyl-CoA desaturase delta-6-desaturase like 2, LLCDL 2, LLCDL2, SLL0262, TU 13, TU13, FADS2_HUMAN.

Background: Members of the fatty acid desaturase (FADS) family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway. Members of this family share N-terminal cytochrome b5-like domains, C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs. FADS2 (fatty acid desaturase 2), also known as D6D, DES6, LLCDL2 or TU13, is a 444 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one cytochrome b5 heme-binding domain. Expressed in adult and fetal heart and in adult liver, brain, lung and retina, FADS2 functions as a component of a lipid metabolic pathway and catalyzes the first step in the pathway, namely the formation of unsaturated fatty acids from polyunsaturated fatty acids. Defects in the gene encoding FADS2 are the cause of cause of fatty acid delta-6-desaturase deficiency, an affliction that is characterized by skin abnormalities, corneal ulceration and growth failure. Multiple isoforms of FADS2 exist due to alternative splicing events.