FOXG1 anticorps (AA 201-300) (Biotin)

N° du produit ABIN1391977

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXG1 dans WB et ELISA. Il présente une réactivité envers Rat.

Aperçu rapide pour FOXG1 anticorps (AA 201-300) (Biotin) (ABIN1391977)

Antigène: FOXG1 (Forkhead Box G1 (FOXG1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXG1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-FOXG1 anticorps (Biotin)

Épitope: AA 201-300

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOXG1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FOXG1

Antigène: FOXG1 (Forkhead Box G1 (FOXG1))

Autre désignation: FOXG1/BF-1

Sujet:

Synonyms: BF 1, BF 2, BF-1, BF-2, BF1, BF2 , Brain factor 1, Brain factor 2, FHKL, FKH2, FKHL1, FKHL2, FKHL2, FKHL3, FKHL4, Forkhead box G1A, Forkhead box G1B, Forkhead box protein G1, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead drosophila homolog like 2, Forkhead like 1, Forkhead like 2, FOXG1_HUMAN.

Background: The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (14). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1).