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WWC1 anticorps (AA 351-450) (FITC)

WWC1 Reactivité: Humain, Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1392056
  • Antigène Voir toutes WWC1 Anticorps
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 36
    • 19
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 34
    • 3
    Lapin
    Clonalité
    • 34
    • 3
    Polyclonal
    Conjugué
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WWC1 est conjugé à/à la FITC
    Application
    • 37
    • 17
    • 12
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human KIBRA
    Isotype
    IgG
    Top Product
    Discover our top product WWC1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    Autre désignation
    KIBRA (WWC1 Produits)
    Synonymes
    anticorps CG12600, anticorps CG33967, anticorps CG7552, anticorps Dmel\\CG33967, anticorps Kibra, anticorps ORE-2, anticorps RE26350, anticorps kib, anticorps l(3)02404, anticorps l(3)j5C3, anticorps l(3)neo42, anticorps HBEBP3, anticorps HBEBP36, anticorps KIBRA, anticorps AA408228, anticorps AU017197, anticorps BC037006, anticorps mKIAA0869, anticorps CG33967 gene product from transcript CG33967-RB, anticorps WW and C2 domain containing 1, anticorps WW, C2 and coiled-coil domain containing 1, anticorps kibra, anticorps WWC1, anticorps Wwc1
    Sujet

    Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869

    Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

    ID gène
    23286
    UniProt
    Q8IX03
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