PDE7A anticorps (AbBy Fluor® 488)

N° du produit ABIN1392082

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE7A dans IF (p). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour PDE7A anticorps (AbBy Fluor® 488) (ABIN1392082)

Antigène: PDE7A (phosphodiesterase 7A (PDE7A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE7A est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PDE7A anticorps (AbBy Fluor® 488)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDE7A

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détails sur PDE7A

Antigène: PDE7A (phosphodiesterase 7A (PDE7A))

Autre désignation: Pde7a

Sujet:

Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

Synonyms: HCP 1, HCP1, High affinity cAMP specic 3'5' cyclic phosphodiesterase 7A, High affinity cAMP-specic 3'', P2A, PDE 7, PDE 7A, PDE7, PDE71, PDE7A, PDE7A_HUMAN, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, Phosphodiesterase7A, Rolipram insensitive phosphodiesterase type 7, TM 22, TM22, 5''-cyclic phosphodiesterase 7A.

Pathways: cAMP Metabolic Process