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COQ10B anticorps (AA 38-110) (Biotin)

COQ10B Reactivité: Humain, Souris WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1392565
  • Antigène Voir toutes COQ10B Anticorps
    COQ10B (Coenzyme Q10 Homolog B (COQ10B))
    Épitope
    • 14
    • 1
    • 1
    AA 38-110
    Reactivité
    • 18
    • 16
    • 2
    Humain, Souris
    Hôte
    • 18
    • 1
    Lapin
    Clonalité
    • 18
    • 1
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COQ10B est conjugé à/à la Biotin
    Application
    • 18
    • 13
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human COQ10B
    Isotype
    IgG
    Top Product
    Discover our top product COQ10B Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    COQ10B (Coenzyme Q10 Homolog B (COQ10B))
    Autre désignation
    COQ10B (COQ10B Produits)
    Synonymes
    anticorps 1500041J02Rik, anticorps 1700030I21Rik, anticorps 9530077A17Rik, anticorps AV002237, anticorps AW742641, anticorps RGD1359509, anticorps fc38f07, anticorps im:6912267, anticorps wu:fc38f07, anticorps zgc:112103, anticorps coenzyme Q10B, anticorps COQ10B, anticorps Coq10b, anticorps coq10b
    Sujet

    Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.

    Background: COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.

    ID gène
    80219
    UniProt
    Q9H8M1
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