NERP-1 anticorps (AA 231-330) (Biotin)

N° du produit ABIN1393369

Détail du produit anti-NERP-1 anticorps (Biotin)

Antigène: NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))

Épitope: AA 231-330

Reactivité: Souris, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NERP-1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat, Poisson zèbre (Danio rerio)

Homologie: Human,Cow,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NERP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NERP-1

Antigène: NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))

Autre désignation: VGF/NERP-1 (NERP-1 Produits)

Synonymes: anticorps Gm1052, anticorps VGF nerve growth factor inducible, anticorps VGF, anticorps Vgf

Sujet:

Synonyms: Nerve growth factor inducible, Neurosecretory protein VGF, VGF, VGF_HUMAN, SCG7, SgVII, Neuroendocrine regulatory peptide-1, NERP-1, NERP1

Background: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

ID gène: 7425

UniProt: O15240