NETO2 anticorps (AA 151-250) (Biotin)

N° du produit ABIN1393969

Cet anticorps Lapin Polyclonal détecte spécifiquement NETO2 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour NETO2 anticorps (AA 151-250) (Biotin) (ABIN1393969)

Antigène: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NETO2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NETO2 anticorps (Biotin)

Épitope: AA 151-250

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NETO2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NETO2

Antigène: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Autre désignation: NETO2

Sujet:

Synonyms: Brain specic transmembrane protein, Brain specic transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2, Brain-specic transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, FLJ10430, FLJ14724, FLJ90456, NEOT2, NETO 2, Neto2, NETO2_HUMAN, Neuropilin NRP and tolloid TLL like 2, Neuropilin and tolloid like protein 2, Neuropilin and tolloid-like protein 2.

Background: NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.