ACBD3 anticorps (AA 65-160) (Biotin)

N° du produit ABIN1394053

Cet anticorps Lapin Polyclonal détecte spécifiquement ACBD3 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour ACBD3 anticorps (AA 65-160) (Biotin) (ABIN1394053)

Antigène: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACBD3 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ACBD3 anticorps (Biotin)

Épitope: AA 65-160

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ACBD3/GOCAP1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ACBD3

Antigène: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Autre désignation: ACBD3

Sujet:

Synonyms: ACBD 3, ACBD3, Acyl CoA binding domain containing protein 3, Acyl Coenzyme A binding domain containing 3, Acyl-CoA-binding domain-containing protein 3, GCP 60, GCP60, GCP60_HUMAN, GOCAP 1, GOCAP1, Golgi complex associated protein 1 60 kDa, Golgi complex associated protein 1, Golgi complex-associated protein 1, Golgi phosphoprotein 1, Golgi resident protein GCP60, GOLPH 1, GOLPH1, PAP 7, PAP7, PBR and PKA associated protein 7, PBR associated protein, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor associated protein PAP7, Peripheral benzodiazepine receptor-associated protein PAP7, Peripherial benzodiazepine receptor associated protein, PKA RIalpha associated protein.

Background: ACBD3 (acyl-CoA-binding domain-containing protein 3), also known as GCP60 (Golgi resident protein GCP60), GOCAP1, PAP7 or GOLPH1, is a Golgi apparatus membrane protein that contains one ACB (acyl-CoA-binding) domain and one GOLD (Golgi dynamics) domain which is essential for its interaction with other proteins. Expressed ubiquitously with highest expression in ovary and testis, ACBD3 is responsible for maintaining Golgi structure and, through binding to Giantin (golgin subfamily B member 1), functions to mediate protein transport between the Golgi and the endoplasmic reticulum (ER). Changes in the subcellular location of ACBD3 trigger signaling cascades within the Golgi that regulate cell fate and cell cycle progression. Additionally, ACBD3 is thought to act as a peripheral-type benzodiazepine receptor-associated protein, possibly playing a role in hormonal regulation and steroid formation.