RILPL2 anticorps (AA 111-211) (Biotin)

N° du produit ABIN1394239

Cet anticorps Lapin Polyclonal détecte spécifiquement RILPL2 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour RILPL2 anticorps (AA 111-211) (Biotin) (ABIN1394239)

Antigène: RILPL2 (Rab Interacting Lysosomal Protein-Like 2 (RILPL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RILPL2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RILPL2 anticorps (Biotin)

Épitope: AA 111-211

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RILPL2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RILPL2

Antigène: RILPL2 (Rab Interacting Lysosomal Protein-Like 2 (RILPL2))

Autre désignation: RILPL2

Sujet:

Synonyms: FLJ30380, FLJ32372, MGC7036, p40phox-binding protein, Rab-interacting lysosomal protein-like 2, RILP-like protein 2, RILPL2, RIPL2_HUMAN, RLP2, Rab interacting lysosomal protein-like 2.

Background: RILPL2 is a 211 amino acid protein that belongs to the RILPL family. RILPL2 does not regulate lysosomal morphology or distribution. RILPL2 shares 32 % and 18 % amino acid identity with RILPL1 and RILP, respectively. RILPL2 as a novel interacting partner for the actin-based molecular motor MyoVa, and has a novel role for RILPL2 in controlling neuronal morphogenesis. It has been suggested that there is also a novel role for RILPL2 in the regulation of cellular shape and dendritic-spine morphogenesis, probably via the Rac1-Pak pathway. PCR analysis of human tissues detects highest RILPL2 expression in lung, followed by placenta. Lower expression is detected in liver, kidney, pancreas, heart and brain, but no expression is detected in skeletal muscle. The RILPL2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 12q24.31.