Snail + Slug (pSer246) anticorps (AbBy Fluor® 350)

N° du produit ABIN1394343

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans FACS. Adapté pour Humain.

Aperçu rapide pour Snail + Slug (pSer246) anticorps (AbBy Fluor® 350) (ABIN1394343)

Antigène: Snail + Slug

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: AbBy Fluor® 350

Application: Flow Cytometry (FACS)

Détail du produit

Épitope: pSer246

Réactivité croisée: Humain

Homologie: Mouse,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SNAIL around the phosphorylation site of Ser246

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Snail + Slug

Sujet:

Synonyms: SNAIL + SLUG phospho S246 + S251, SNAIL + SLUG phospho Ser246 + Ser251, SNAILSer246 + SLUGSer251, dJ710H13.1, MGC10182, Neural crest transcription factor Slug, Protein sna, Protein snail homolog 1, Protein snail homolog 2, Protein snail homolog, Slug homolog zinc finger protein, Slug zinc finger protein, SLUGH, SLUGH 1, SLUGH1, SLUGH2, SNA, Sna protein, SNAH, SNAI 2, snai1, SNAI1_HUMAN, Snai2, SNAI2_HUMAN, Snail 2, Snail homolog 1 Drosophila, Snail homolog 2, Snail2, WS 2D, WS2D, Zinc finger protein SLUG, Zinc finger protein SNAI1, Zinc finger protein SNAI2.

Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin. SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation. SLUG also has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene).

ID gène: 6311

UniProt: O95863