UNCX anticorps (AA 145-150) (Biotin)

N° du produit ABIN1394833

Cet anticorps Lapin Polyclonal détecte spécifiquement UNCX dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour UNCX anticorps (AA 145-150) (Biotin) (ABIN1394833)

Antigène: UNCX (UNC Homeobox (UNCX))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNCX est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-UNCX anticorps (Biotin)

Épitope: AA 145-150

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UNCX

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur UNCX

Antigène: UNCX (UNC Homeobox (UNCX))

Autre désignation: UNCX

Sujet:

Synonyms: Homeobox protein unc-4 homolog, Homeobox protein Uncx4.1, tcag7.1272, UNC homeobox, Unc4.1 homeobox, UNC4_HUMAN, Uncx, UNCX4.1.

Background: Members of the paired homeobox family play a role in regulating cell development and pattern formation during embryonic stages. UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.