P2X5b (AA 261-360) anticorps (Biotin)

N° du produit ABIN1395211

Cet anticorps Lapin Polyclonal détecte spécifiquement P2X5b dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour P2X5b (AA 261-360) anticorps (Biotin) (ABIN1395211)

Antigène: P2X5b

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 261-360

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human P2X5b

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: P2X5b

Sujet:

Synonyms: ATP receptor, ATP receptor subunit, ionotropic ATP receptor P2X5, MGC47755, P2RX5, P2X purinoceptor 5, P2X5, P2X5R, Purinergic receptor, Purinergic receptor P2X ligand gated ion channel 5, P2RX5_HUMAN.

Background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.