DLGAP2 anticorps (AA 251-360) (Biotin)

N° du produit ABIN1395391

Cet anticorps Lapin Polyclonal détecte spécifiquement DLGAP2 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour DLGAP2 anticorps (AA 251-360) (Biotin) (ABIN1395391)

Antigène: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DLGAP2 anticorps (Biotin)

Épitope: AA 251-360

Réactivité croisée: Humain, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DLGAP2

Antigène: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Autre désignation: SAPAP2/DLGAP2

Sujet:

Synonyms: DAP-2, DAP2, Discs large Drosophila homolog associated protein 2, Discs large homolog associated protein 2, Disks large-associated protein 2, Dlgap2, DLGP2_HUMAN, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2, hide.

Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.