PATJ anticorps (AA 1001-1200) (Biotin)

N° du produit ABIN1395409

Détail du produit anti-PATJ anticorps (Biotin)

Antigène: PATJ (INADL) (InaD-Like (INADL))

Épitope: AA 1001-1200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PATJ est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PATJ

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PATJ

Antigène: PATJ (INADL) (InaD-Like (INADL))

Autre désignation: PATJ (INADL Produits)

Synonymes: anticorps wu:fc76h08, anticorps si:dz129i22.4, anticorps si:busm1-129i22.4, anticorps Cipp, anticorps InaD-like, anticorps PATJ, anticorps hINADL, anticorps Patj, anticorps Inadl2, anticorps RGD1565362, anticorps PATJ, crumbs cell polarity complex component, anticorps patj, anticorps PATJ, anticorps Patj

Sujet:

Synonyms: Channel interacting PDZ domain protein, Cipp, FLJ26982, hINADL, Inactivation no after potential D like protein, INAD like, InaD like Drosophila, INAD like protein, INADL, INADL protein, PALS 1 associated tight junction protein, PALS1 associated tight junction protein, PATJ, PDZ domain protein, PDZ domain protein Drosophila inaD like, Post synaptic density 95 / discs large / zonula occludens 1 domain protein, Protein associated to tight junctions, INADL_HUMAN .

Background: The membranes of myelinating Schwann cells are joined by tight, gap and adherens junctions, all of which are found in regions of noncompact myelin: the paranodal loops, incisures of Schmidt-Lanterman and mesaxons. Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes. Pals-associated tight junction protein (PATJ), the human homolog of Drosophila Discs Lost, is differentially localized in myelinating Schwann cells. PATJ associates with Claudin-1, CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), and Pals1 (a Lin-7 associated protein). The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity.