Calcyphosine anticorps (AA 101-189) (AbBy Fluor® 555)

N° du produit ABIN1395515

L’anticorps Lapin Polyclonal anti-Calcyphosine a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter Calcyphosine dans des échantillons de Humain.

Aperçu rapide pour Calcyphosine anticorps (AA 101-189) (AbBy Fluor® 555) (ABIN1395515)

Antigène: Calcyphosine (CAPS)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calcyphosine est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Calcyphosine anticorps (AbBy Fluor® 555)

Épitope: AA 101-189

Réactivité croisée: Humain

Homologie: Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calcyphosine 1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Calcyphosine

Antigène: Calcyphosine (CAPS)

Autre désignation: Calcyphosine 1/CAPS1

Sujet:

Synonyms: Calcyphosin, Calcyphosine 1, Calcyphosine, CAPS, CAPS1, CAYP1_HUMAN, Thyroid protein p24.

Background: CAPS1 is a 189 amino acid cytoplasmic protein that contains four EF-hand domains, which serve as calcium-binding sites, and was first identified in canine thyroid. Interestingly, CAPS1 is much less abundant in humans than in canines. Synthesis and phosphorylation of CAPS1 is upregulated by cAMP-agonists in thyrocytes. CAPS1 likely functions in the regulation of ionic transport and may be involved in cross-signaling between cAMP and Ca(+2)-phophatidylinositol cascades. In addition to thyriod, CAPS1 is expressed in brain, salivary glands and lung. Expression of CAPS1 is increased in endometrial cancer and prognosis seems to be dependent on the level of CAPS1 expression, indicating that CAPS1 may be an appropriate prognostic marker for patient survival.