UTF1 anticorps (AA 101-170) (FITC)

N° du produit ABIN1395788

L’anticorps anti-UTF1 Polyclonal produit chez le Lapin a été validé pour WB, IF (cc) et IF (p). Il convient pour la détection de UTF1 dans des échantillons provenant de Humain. }

Aperçu rapide pour UTF1 anticorps (AA 101-170) (FITC) (ABIN1395788)

Antigène: UTF1 (Undifferentiated Embryonic Cell Transcription Factor 1 (UTF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UTF1 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-UTF1 anticorps (FITC)

Épitope: AA 101-170

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UTF1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur UTF1

Antigène: UTF1 (Undifferentiated Embryonic Cell Transcription Factor 1 (UTF1))

Autre désignation: UTF1

Sujet:

Synonyms: hUTF 1, hUTF1, Undferentiated embryonic cell transcription factor 1, UTF 1, UTF1, UTF1_HUMAN.

Background: UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64 % homology with its mouse counterpart, suggesting a similar role between species. The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

ID gène: 8433