KCNJ10 anticorps (Biotin)

N° du produit ABIN1396080

Cet anticorps anti-KCNJ10 Polyclonal Lapin conjugué à Biotin (ABIN1396080) détecte spécifiquement KCNJ10 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour KCNJ10 anticorps (Biotin) (ABIN1396080)

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ10 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KCNJ10 anticorps (Biotin)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Kir4.1

Isotype: IgG

Information d'application

Indications d'application: WB: (1:100-1000), IHC-P: (1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4 °C for 12 months.

Date de péremption: 12 months

Détails sur KCNJ10

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Autre désignation: Kir4.1

Sujet: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Downs syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.
Synonyms: ATP dependent inwardly rectying potassium channel Kir4.1, ATP sensitive inward rectier potassium channel 10, ATP-dependent inwardly rectying potassium channel Kir4.1, ATP-sensitive inward rectier potassium channel 10, BIRK10, Glial ATP dependent inwardly rectying potassium channel KIR4.1, Inward rectier K+ channel Kir1.2, Inward rectier K+ channel KIR1.2, Inwardly rectying potassium channel Kir1.2, inwardly rectying subfamily J member 10, KCNJ 10, Kcnj10, KCNJ13 PEN, KIR1.2, KIR4.1, Potassium channel, Potassium channel inwardly rectying subfamily J member 10, Potassium inwardly rectying channel subfamily J member 10, SESAME, IRK10_HUMAN.
Subcellular locations: Extracellular

ID gène: 3766

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity