Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ATXN3L anticorps (AA 251-355) (FITC)

ATXN3L Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1396645
  • Antigène Voir toutes ATXN3L Anticorps
    ATXN3L (Ataxin 3-Like (ATXN3L))
    Épitope
    AA 251-355
    Reactivité
    • 17
    • 1
    Humain
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATXN3L est conjugé à/à la FITC
    Application
    • 17
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ATXN3L
    Isotype
    IgG
    Top Product
    Discover our top product ATXN3L Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ATXN3L (Ataxin 3-Like (ATXN3L))
    Autre désignation
    ATXN3L (ATXN3L Produits)
    Synonymes
    anticorps MJDL, anticorps ataxin 3 like, anticorps ATXN3L
    Sujet

    Synonyms: ATX3L_HUMAN, ATXN3L, Machado-Joseph disease protein 1-like, MJDL, Putative ataxin-3-like protein.

    Background: Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3) , also known as Machado-Joseph disease (MJD). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region. Longer expansions result in earlier onset and more severe clinical manifestations of the disease.

    ID gène
    92552
Vous êtes ici:
Support technique