RDH13 anticorps (AA 101-200) (Biotin)

N° du produit ABIN1398475

Cet anticorps Lapin Polyclonal détecte spécifiquement RDH13 dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Souris.

Aperçu rapide pour RDH13 anticorps (AA 101-200) (Biotin) (ABIN1398475)

Antigène: RDH13 (Retinol Dehydrogenase 13 (All-Trans and 9-Cis) (RDH13))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RDH13 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RDH13 anticorps (Biotin)

Épitope: AA 101-200

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RDH13

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RDH13

Antigène: RDH13 (Retinol Dehydrogenase 13 (All-Trans and 9-Cis) (RDH13))

Autre désignation: RDH13

Sujet:

Synonyms: RDH13, RDH13_HUMAN, Retinol dehydrogenase 13 all trans and 9 cis, Retinol dehydrogenase 13 all trans/9 cis, Retinol dehydrogenase 13.

Background: RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.

ID gène: 112724