FGFR1OP2 anticorps (AA 51-150) (AbBy Fluor® 555)
Aperçu rapide pour FGFR1OP2 anticorps (AA 51-150) (AbBy Fluor® 555) (ABIN1398545)
Antigène
Voir toutes FGFR1OP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 51-150
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Homologie
- Human,Mouse,Rat,Dog,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human FGFR1OP2
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- FGFR1OP2 (FGFR1 Oncogene Partner 2 (FGFR1OP2))
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Autre désignation
- FGFR1OP2
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Sujet
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Synonyms: DKFZp564O1863, FGFR1 oncogene partner 2, HSPC123, HSPC123 like, FGOP2_HUMAN.
Background: FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12,8)(p11,p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
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ID gène
- 26127
Antigène
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