FBXW2 anticorps (AA 321-420) (Biotin)

N° du produit ABIN1398829

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXW2 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour FBXW2 anticorps (AA 321-420) (Biotin) (ABIN1398829)

Antigène: FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FBXW2 anticorps (Biotin)

Épitope: AA 321-420

Homologie: Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FbxW2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FBXW2

Antigène: FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))

Autre désignation: FbxW2

Sujet:

Synonyms: F box and WD 40 domain containing protein 2, F box and WD repeat domain containing 2, F Box and WD40 Domain Protein 2, F box/WD repeat containing protein 2, FBW 2, FBW2, FBXW 2, Fwd2, Md6, Protein MD6.

Background: F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.

ID gène: 26190