GLIPR2 anticorps (AA 51-154) (AbBy Fluor® 488)

N° du produit ABIN1398928

Cet anticorps Lapin Polyclonal détecte spécifiquement GLIPR2 dans IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour GLIPR2 anticorps (AA 51-154) (AbBy Fluor® 488) (ABIN1398928)

Antigène: GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLIPR2 est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GLIPR2 anticorps (AbBy Fluor® 488)

Épitope: AA 51-154

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GLIPR2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GLIPR2

Antigène: GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))

Autre désignation: GLIPR2

Sujet:

Synonyms: GAPR 1, GAPR-1, GAPR1_HUMAN, GLI pathogenesis related 2, Glioma pathogenesis related protein 2, Glioma pathogenesis-related protein 2, GliPR 2, GLIPR2, Golgi associated plant pathogenesis related protein 1, Golgi associated PR 1 protein, Golgi-associated plant pathogenesis-related protein 1, Golgi-associated PR-1 protein, OTTMUSP00000007558, RP11-421H8.5, RP23-209M8.2, C77180, 5730414A08Rik, C9orf19.

Background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.