Lin28A/ B (AA 75-180) anticorps (AbBy Fluor® 555)

N° du produit ABIN1399121

L’anticorps anti-Lin28A/ B Polyclonal Lapin est utilisé pour la détection de Lin28A/ B dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF (cc) et IF (p).

Aperçu rapide pour Lin28A/ B (AA 75-180) anticorps (AbBy Fluor® 555) (ABIN1399121)

Antigène: Lin28A/ B

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 75-180

Specificité: This antibody is produced using synthetic peptide that falls within the range of 90-120 amino acids of human Lin28A. Due to 92 % sequence similarity, this antibody may cross react with Lin28B.

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Lin28A

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Lin28A/ B

Autre désignation: Lin28A/B

Sujet:

Synonyms: Protein lin-28 homolog A, LIN28A, Lin-28A, Zinc finger CCHC domain-containing protein 1, CSDD1, LIN28, ZCCHC1, Protein lin-28 homolog B, LIN28B, Lin-28B, CSDD2

Background: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.

ID gène: 79727, 389421

UniProt: Q6ZN17