APLP2 anticorps (AA 501-600) (Biotin)

N° du produit ABIN1399231

Cet anticorps Lapin Polyclonal détecte spécifiquement APLP2 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour APLP2 anticorps (AA 501-600) (Biotin) (ABIN1399231)

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-APLP2 anticorps (Biotin)

Épitope: AA 501-600

Homologie: Human,Mouse,Rat,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APLP2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur APLP2

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Autre désignation: APLP2

Sujet:

Synonyms: amyloid beta A4 precursor like protein 2, Amyloid like protein 2, amyloid precursor protein homolog HSD2, Amyloid protein homolog, Amyloid-like protein 2, APLP-2, Aplp2, APLP2_HUMAN, APPH, APPL2, CDEBP, CDEI box binding protein, CDEI box-binding protein.

Background: APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

ID gène: 334

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour