RFTN2 anticorps (AA 1-100) (Biotin)

N° du produit ABIN1399405

Cet anticorps Lapin Polyclonal détecte spécifiquement RFTN2 dans ELISA, WB, IHC (fro) et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour RFTN2 anticorps (AA 1-100) (Biotin) (ABIN1399405)

Antigène: RFTN2 (Raftlin Family Member 2 (RFTN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFTN2 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RFTN2 anticorps (Biotin)

Épitope: AA 1-100

Homologie: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RFTN2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RFTN2

Antigène: RFTN2 (Raftlin Family Member 2 (RFTN2))

Autre désignation: RFTN2

Sujet:

Synonyms: Raft-linking protein 2, Raftlin-2, Rftn2, RFTN2_HUMAN.

Background: Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene.

ID gène: 130132