MEPE anticorps (AA 201-300) (AbBy Fluor® 647)

N° du produit ABIN1400190

Cet anticorps anti-MEPE est un anticorps Lapin Polyclonal détectant MEPE dans WB, IF (cc) et IF (p). Adapté pour Souris.

Aperçu rapide pour MEPE anticorps (AA 201-300) (AbBy Fluor® 647) (ABIN1400190)

Antigène: MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEPE est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MEPE anticorps (AbBy Fluor® 647)

Épitope: AA 201-300

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MEPE

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MEPE

Antigène: MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))

Autre désignation: MEPE

Sujet:

Synonyms: Matrix extracellular phosphoglycoprotein, MEPE, MEPE_HUMAN, OF45, Osteoblast/osteocyte factor 45.

Background: MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers.

ID gène: 56955