TRIM17 / RNF16 anticorps (AbBy Fluor® 647)
Aperçu rapide pour TRIM17 / RNF16 anticorps (AbBy Fluor® 647) (ABIN1401186)
Antigène
Voir toutes TRIM17 / RNF16 (TRIM17) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human TRIM17/RNF16
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Isotype
- IgG
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Indications d'application
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- TRIM17 / RNF16 (TRIM17)
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Autre désignation
- RNF16
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Sujet
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Synonyms: RBCC, RING finger protein 16, RNF16, TERF, Testis RING finger protein, TRIM 17, Tripartite mot protein 17, TRI17_HUMAN.
Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM17 (tripartite motif-containing 17), also known as RBCC, terf or RNF16, is a 477 amino acid protein that contains one RING-type zinc finger, one SPRY domain and one B box-type zinc finger. Expressed nearly exclusively in testis, TRIM17 belongs to the TRIM family and, based on its functional domains, may play a role in transcriptional regulation events. The gene encoding TRIM17 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
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ID gène
- 51127
Antigène
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