MLF1 anticorps (Biotin)

N° du produit ABIN1401295

Détail du produit anti-MLF1 anticorps (Biotin)

Antigène: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLF1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MLF1/2/3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MLF1

Antigène: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Autre désignation: MLF1 (MLF1 Produits)

Synonymes: anticorps MLF1, anticorps HLS7, anticorps myeloid leukemia factor 1, anticorps myeloid leukemia factor 1 L homeolog, anticorps MLF1, anticorps mlf1.L, anticorps mlf1, anticorps Mlf1

Sujet:

Synonyms: Hls7, MLF1, MLF2, MLF3, MLF1_HUMAN, Myelodysplasia myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1, myeloid leukemia factor 1 variant 1, myeloid leukemia factor 1 variant 2, myeloid leukemia factor 1 variant 3.

Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

ID gène: 4291