PACRG anticorps (Biotin)

N° du produit ABIN1401859

Détail du produit anti-PACRG anticorps (Biotin)

Antigène: PACRG (PARK2 Co-Regulated (PACRG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PACRG est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PACRG

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PACRG

Antigène: PACRG (PARK2 Co-Regulated (PACRG))

Autre désignation: PACRG (PACRG Produits)

Synonymes: anticorps PACRG, anticorps GLUP, anticorps HAK005771, anticorps PARK2CRG, anticorps RP3-495O10.2, anticorps zgc:101786, anticorps RGD1561027, anticorps 1700008H23Rik, anticorps parkin coregulated, anticorps PARK2 co-regulated, anticorps PARK2 coregulated, anticorps PACRG, anticorps pacrg, anticorps Pacrg

Sujet:

Synonyms: GLUP, Molecular chaperone/chaperonin binding protein, PARK 2 co regulated, PARK 2 coregulated, PARK2 co regulated, PARK2 coregulated, PARK2CRG, Parkin co regulated gene protein, Parkin Co-regulated Gene, Parkin coregulated gene protein, RP3 495O10.2, PACRG_HUMAN.

Background: The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26, Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.

ID gène: 135138