CHAF1A anticorps (Biotin)

N° du produit ABIN1402447

Détail du produit anti-CHAF1A anticorps (Biotin)

Antigène: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHAF1A est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human p150 CAF1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CHAF1A

Antigène: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Autre désignation: p150 CAF1 (CHAF1A Produits)

Synonymes: anticorps CHAF1A, anticorps CAF-1, anticorps CAF1, anticorps CAF1B, anticorps CAF1P150, anticorps P150, anticorps AL023013, anticorps AL024058, anticorps Cac1p, anticorps CAF-1P150, anticorps CAF-I-p150, anticorps CAF-Ip150, anticorps caip150, anticorps wu:fd14g10, anticorps zgc:153930, anticorps chaf1a-b, anticorps xp150, anticorps chromatin assembly factor 1 subunit A, anticorps chromatin assembly factor 1, subunit A (p150), anticorps chromatin assembly factor 1 subunit A S homeolog, anticorps Chaf1a, anticorps CHAF1A, anticorps LOC100447657, anticorps chaf1a, anticorps chaf1a.S

Sujet:

Synonyms: CAF-1 p150, CAF 1 150 kDa subunit, CAF 1, CAF 1 subunit A, CAF, CAF I 150 kDa subunit, CAF I p150, CAF Ip150, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, CAF1 150 kDa subunit, CAF1, CAF1 p150 Subunit, CAF1 subunit A, CAF1A, CAF1A, CAF1A_HUMAN, CAF1B, CAF1P150, CAF1P155, CAF1P155, CHAF1A, Chromatin assembly factor 1 subunit A, Chromatin Assembly Factor 1 Subunit A p150, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I 150 kDa, Chromatin Assembly Factor I, Chromatin assembly factor I p150 subunit, DCAF1, hp150, Nucleosome Remodeling Factor 150 kDa Subunit, NURF150, P150.

Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcription regulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

ID gène: 10036