MYLIP anticorps (AA 65-103) (FITC)

N° du produit ABIN1404014

L’anticorps anti-MYLIP Polyclonal Lapin est utilisé pour la détection de MYLIP dans des échantillons de Humain. Il a été validé pour WB et IF (p).

Aperçu rapide pour MYLIP anticorps (AA 65-103) (FITC) (ABIN1404014)

Antigène: MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLIP est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MYLIP anticorps (FITC)

Épitope: AA 65-103

Fonction: MYLIP Polyclonal Antibody, FITC Conjugated

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MYLIP

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MYLIP

Antigène: MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))

Autre désignation: MYLIP

Sujet:

Synonyms: MIR, IDOL, E3 ubiquitin-protein ligase MYLIP, Inducible degrader of the LDL-receptor, Myosin regulatory light chain interacting protein, MYLIP, BZF1, BM-023, PP5242

Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

ID gène: 29116

UniProt: Q8WY64