GID8/C20orf11 anticorps (AbBy Fluor® 488)

N° du produit ABIN1404100

Cet anticorps Lapin Polyclonal détecte spécifiquement GID8/C20orf11 dans WB et IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GID8/C20orf11 anticorps (AbBy Fluor® 488) (ABIN1404100)

Antigène: GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GID8/C20orf11 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GID8/C20orf11 anticorps (AbBy Fluor® 488)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TWA1/C20orf11

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GID8/C20orf11

Antigène: GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))

Autre désignation: C20orf11

Sujet:

Synonyms: Chromosome 20 open reading frame 11, CT011_HUMAN, Protein C20orf11, Twa1, Two hybrid associated protein 1, Two hybrid-associated protein 1 with Ran BP-M, Two hybrid associated protein 1 with RanBPM, Two hybrid-associated protein 1 with RanBPM.

Background: TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2 % of the human genome and contains nearly 63 million bases that encode over 600 genes.