ITM2A anticorps (AA 73-123) (AbBy Fluor® 488)

N° du produit ABIN1404196

Cet anticorps Lapin Polyclonal détecte spécifiquement ITM2A dans WB, FACS et IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ITM2A anticorps (AA 73-123) (AbBy Fluor® 488) (ABIN1404196)

Antigène: ITM2A (Integral Membrane Protein 2A (ITM2A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITM2A est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ITM2A anticorps (AbBy Fluor® 488)

Épitope: AA 73-123

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ITM2A

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ITM2A

Antigène: ITM2A (Integral Membrane Protein 2A (ITM2A))

Autre désignation: ITM2A

Sujet:

Synonyms: E25A, BRICD2A, Integral membrane protein 2A, Protein E25, ITM2A, UNQ603/PRO1189

Background: The type II integral membrane (ITM2) protein family consists of three members ITM2A (also designated E25), ITM2B and ITM2C. ITM2A expression is high in osteogenic and lymphoid tissues, while both ITM2B and ITM2C are expressed in brain. Mutations in the ITM2B gene can lead to familial British dementia (fbd), and autosomal dominant disease characterized by progressive dementia, spasticity, and cerebellar ataxia, or familial Danish dementia (fdd), an autosomal dominant disorder characterized by cataracts, deafness, progressive ataxia, and dementia. The ITM2A 263-amino acid protein contains an N-terminal cytosolic domain, an uncleaved signal anchor sequence, and a tyrosine-rich C-terminal domain. Human ITM2A shares 91 % homology with mouse ITM2A.

ID gène: 9452

UniProt: O43736