ANKMY1 anticorps (Biotin)

N° du produit ABIN1404415

Cet anticorps Lapin Polyclonal détecte spécifiquement ANKMY1 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour ANKMY1 anticorps (Biotin) (ABIN1404415)

Antigène: ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1 (ANKMY1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKMY1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ANKMY1 anticorps (Biotin)

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ANKMY1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ANKMY1

Antigène: ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1 (ANKMY1))

Autre désignation: ANKMY1

Sujet:

Synonyms: ankyrin repeat and MYND domain containing 1, Testis specic ankyrin like protein 1, TSAL1, Zinc finger MYND domain containing protein 13, ZMYND13, ANKY1_HUMAN.

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events.

ID gène: 51281