Biogenesis of Lysosome-Related Organelles Complex 1 Subunit 6 (BLOC1S6) anticorps (Biotin)

N° du produit ABIN1404955

Cet anticorps Lapin Polyclonal détecte spécifiquement Biogenesis of Lysosome-Related Organelles Complex 1 Subunit 6 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Biogenesis of Lysosome-Related Organelles Complex 1 Subunit 6 (BLOC1S6) anticorps (Biotin) (ABIN1404955)

Antigène: Biogenesis of Lysosome-Related Organelles Complex 1 Subunit 6 (BLOC1S6)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Fonction: C17orf59 Polyclonal Antibody, Biotin Conjugated

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C17orf59

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-500), IHC-P(1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Biogenesis of Lysosome-Related Organelles Complex 1 Subunit 6 (BLOC1S6)

Autre désignation: C17orf59

Sujet:

Synonyms: Chromosome 17 open reading frame 59, CQ059_HUMAN, FLJ20014, PRO2472, Uncharacterized protein C17orf59.

Background: C17orf59 is a 357 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

ID gène: 54785