HCN3 anticorps (Biotin)

N° du produit ABIN1405063

Cet anticorps Lapin Polyclonal détecte spécifiquement HCN3 dans WB et IHC (p). Il présente une réactivité envers Rat, Humain et Souris.

Aperçu rapide pour HCN3 anticorps (Biotin) (ABIN1405063)

Antigène: HCN3 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCN3 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HCN3 anticorps (Biotin)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HCN3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur HCN3

Antigène: HCN3 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3))

Autre désignation: HCN3

Sujet:

Synonyms: Hcn3, HCN3_HUMAN, hyperpolarization activated cyclic nucleotide-gated potassium channel 3, KIAA1535, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

Background: Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. HCN3 contains a segment characterized by a series of positively charged amino acids at every third position. This region designated S4 is likely to be the voltage sensor of the protein. In the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively.

ID gène: 57657