PAPPA2 anticorps (Biotin)

N° du produit ABIN1405423

Cet anticorps Lapin Polyclonal détecte spécifiquement PAPPA2 dans WB et IHC (p). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour PAPPA2 anticorps (Biotin) (ABIN1405423)

Antigène: PAPPA2 (Pappalysin 2 (PAPPA2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAPPA2 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PAPPA2 anticorps (Biotin)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PAPP A2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PAPPA2

Antigène: PAPPA2 (Pappalysin 2 (PAPPA2))

Autre désignation: PAPP A2

Sujet:

Synonyms: PAPPA 2, PAPP E, PAPP-A2, PAPP-E, PAPP2_HUMAN, PAPPA 2, PAPPA2, Pappalysin 2, Pappalysin-2, PLAC3, Pregnancy associated plasma protein A2, Pregnancy associated plasma protein E1, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1.

Background: Pregnancy-associated plasma protein-A (Pappalysin-1 or PAPP-A), also known as Insulin-like growth factor-dependent IGF-binding protein 4 (IGFBP4) protease, is a member of the peptidase M43B family of proteins. PAPP-A, a metalloproteinase, cleaves Insulin-like growth factor binding proteins IGFBP4 and IGFBP5, releasing bound IGF. PAPP-A is primarily expressed in septa and anchoring villi in placenta and is also expressed in pregnancy serum. Levels of PAPP-A increase throughout pregnancy. Lower levels of expression can be detected in kidney, prostate, breast, ovary and endometrial tissues. PAPP-A is a secreted protein that can form homodimers, in pregnancy serum PAPP-A may also form a heterotetramer with PRG-2.

ID gène: 60676