BFSP2 anticorps (AA 181-280) (HRP)

N° du produit ABIN1406672

L’anticorps Lapin Polyclonal anti-BFSP2 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter BFSP2 dans des échantillons de Humain.

Aperçu rapide pour BFSP2 anticorps (AA 181-280) (HRP) (ABIN1406672)

Antigène: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BFSP2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BFSP2 anticorps (HRP)

Épitope: AA 181-280

Homologie: Human,Mouse,Rat,Dog

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BFSP2/Phakinin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BFSP2

Antigène: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Autre désignation: Bfsp2/Phakinin

Sujet:

Synonyms: 49 kDa cytoskeletal protein, Beaded filament protein CP49, Beaded filament structural protein 2, Beaded filament structural protein 2, phakinin, Bfps2, Cytoskeletal protein, 49 kD, BFSP2, BFSP2_HUMAN, CP47, CP49, Lens fiber cell beaded filament protein CP 47, Lens fiber cell beaded filament protein CP 49,Lens intermediate filament-like light, LL-L, Phakinin, PHAKOSIN.

Background: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.

ID gène: 3921