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STXBP6 anticorps (AA 1-100) (Cy5)

STXBP6 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1406800
  • Antigène Voir toutes STXBP6 Anticorps
    STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
    Épitope
    • 14
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    AA 1-100
    Reactivité
    • 44
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 1
    Lapin
    Clonalité
    • 44
    Polyclonal
    Conjugué
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STXBP6 est conjugé à/à la Cy5
    Application
    • 33
    • 22
    • 12
    • 12
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Amisyn
    Isotype
    IgG
    Top Product
    Discover our top product STXBP6 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
    Autre désignation
    Amisyn (STXBP6 Produits)
    Synonymes
    anticorps MGC68796, anticorps zgc:86678, anticorps wu:fd20e06, anticorps amisyn, anticorps hspc156, anticorps MGC88977, anticorps STXBP6, anticorps LOC100226852, anticorps BC024598, anticorps C85317, anticorps Amisyn, anticorps syntaxin binding protein 6 L homeolog, anticorps syntaxin binding protein 6 (amisyn), anticorps syntaxin binding protein 6, anticorps stxbp6.L, anticorps stxbp6, anticorps STXBP6, anticorps Stxbp6
    Sujet

    Synonyms: Amisyn, HSPC156, STXB6_HUMAN, STXBP6, Syntaxin binding protein 6, Syntaxin-binding protein 6.

    Background: Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding.

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