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SH3TC2 anticorps (AA 851-950) (Cy3)

SH3TC2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN1407879
  • Antigène Voir toutes SH3TC2 Anticorps
    SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))
    Épitope
    • 14
    • 5
    • 1
    • 1
    AA 851-950
    Reactivité
    • 27
    • 1
    Humain
    Hôte
    • 27
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SH3TC2 est conjugé à/à la Cy3
    Application
    • 15
    • 12
    • 12
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SH3TC2
    Isotype
    IgG
    Top Product
    Discover our top product SH3TC2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))
    Autre désignation
    SH3TC2 (SH3TC2 Produits)
    Synonymes
    anticorps CMT4C, anticorps MNMN, anticorps D430044G18Rik, anticorps RGD1309038, anticorps SH3 domain and tetratricopeptide repeats 2, anticorps SH3TC2, anticorps Sh3tc2
    Sujet

    Synonyms: KIAA1985, CMT4C, D430044G18Rik, FLJ13605, MNMN, PP12494, RGD1309038, S3TC2_HUMAN, SH3 domain and tetratricopeptide repeats-containing protein 2, SH3TC2.

    Background: SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.

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