RECQL5 anticorps (AA 1-100) (HRP)

N° du produit ABIN1407944

L’anticorps Lapin Polyclonal anti-RECQL5 a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter RECQL5 dans des échantillons de Humain.

Aperçu rapide pour RECQL5 anticorps (AA 1-100) (HRP) (ABIN1407944)

Antigène: RECQL5 (RecQ Protein-Like 5 (RECQL5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECQL5 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RECQL5 anticorps (HRP)

Épitope: AA 1-100

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RECQL5

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RECQL5

Antigène: RECQL5 (RecQ Protein-Like 5 (RECQL5))

Autre désignation: RECQL5

Sujet:

Synonyms: ATP-dependent DNA helicase Q5, DNA helicase, RecQ like type 5, DNA helicase, RECQ-like, type 5, RecQ helicase protein-like 5 beta, RecQ protein-like 5, RecQ protein-like 5, isoform CRA_b, RecQ5, Recq5b, Recql5b.

Background: RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higher frequency of SCE. There are three different RecQL5 isoforms - alpha, beta and gamma, produced by alternative splicing.