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Endothelin 2 anticorps (AA 49-59) (HRP)

EDN2 Reactivité: Cat ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1408226
  • Antigène Voir toutes Endothelin 2 (EDN2) Anticorps
    Endothelin 2 (EDN2)
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    AA 49-59
    Reactivité
    • 41
    • 14
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cat
    Hôte
    • 52
    • 3
    Lapin
    Clonalité
    • 53
    • 2
    Polyclonal
    Conjugué
    • 20
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Endothelin 2 est conjugé à/à la HRP
    Application
    • 24
    • 19
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Cat
    Homologie
    Human,Mouse,Rat,Dog,Cow,Cat,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Endolin 2
    Isotype
    IgG
    Top Product
    Discover our top product EDN2 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Endothelin 2 (EDN2)
    Autre désignation
    ET-2/Endothelin 2 (EDN2 Produits)
    Synonymes
    anticorps endothelin-2, anticorps EDN2, anticorps si:ch211-202b2.2, anticorps ET2, anticorps PPET2, anticorps VIC, anticorps Et2, anticorps ET-2, anticorps endothelin 2, anticorps EDN2, anticorps edn2, anticorps Edn2
    Sujet

    Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.

    Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).

    Pathways
    Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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